A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Narender Prasad, D.
- Inhibitory Effects of Ethanolic Extract of Physalis minima on Amylase, Lipase and Alpha Glucosidase
Authors
1 Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, IN
2 Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 2 (2010), Pagination: 159-162Abstract
The aim of the present study was to assess the effects of ethanolic extract of Physalis minima on the amylase, lipase and alpha glucosidase activity in vitro. Powder of whole plant of Physalis minima was extracted in ethanol and the extract was assayed for the measurement of inhibitory effects on activities of enzymes. The extracts rich in bioactive phytochemicals showed inhibitory activity on the amylase, lipase and alpha glucosidase, thus suggesting that extract might be useful in the treatment to limit dietary fat and glucose absorption and the accumulation of fat in adipose tissue. The extracts of Physalis minima may be safe, natural and cost effective for reducing fat and glucose absorption.Keywords
Physalis minima, Amylase, Lipase, Alpha Glucosidase.- Evaluation of Anti Bacterial and Anti Platelet Activity of Ethanolic Leaf Extract of Physalis angulata
Authors
1 Nalanda College of Pharmacy, Nalgonda, A.P, IN
2 Department of Pharmacognosy, Nalanda College of Pharmacy, Cherlapally, Nalgonda-508001 Andhra Pradesh, IN
3 ASN Pharmacy College, Tenali, A.P, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 1 (2010), Pagination: 67-69Abstract
There has always been a closed association between plants and human beings through ancient time and till date. Physalis angulata is an annual herb indigenous to many parts of the tropics, including the Amazon. It can be found on most continents in the tropics, including Africa, Asia, and the Americas. It grows up to 1 m high, bears small, cream-colored flowers, and produces small, light yellowish-orange, edible fruit sometimes referred to as Cutleaf Groundcherry. It is a popular medicine used due to its anti inflammatory effects, anti tumor effects, immunomodulatory effects etc. The present study is to evaluate the anti bacterial and anti platelet activity of the ethanolic leaf extract of Physalis angulata. From the phytochemical screening it was found that the plant is mainly constituted with phenols, steroids and flavonoids .The anti bacterial activity was performed by well diffusion method on various concentrations of the extract. Gentamycin was used as the standard and ethanol as the control. In the antiplatelet activity study, the platelet was induced using adenosine di phosphate. Nephlometer was used to observe the aggregation. It was observed that the ethanolic leaf extract showed pronounced anti platelet activity. But the anti bacterial activity was found to be false positive.